DNA methylation
DNA methylation occurs when methyl groups are added to DNA and can influence how genes are expressed. Methylation patterns change with age and differ among people based on genetics, environment, health and experience.
Biological-age research
Researchers use patterns across many methylation sites to construct ‘epigenetic clocks.’ These are research tools—not a diagnosis, a guarantee of lifespan or proof that an intervention changes health outcomes.
BioVie’s exploratory work
BioVie has analyzed methylation-related signals in samples from bezisterim studies to explore associations among inflammation, cognition and biological-age acceleration. These analyses are exploratory and require independent confirmation.
Development-stage information can change. Investigational candidates are not approved, and safety and efficacy have not been established. Review source documents and current regulatory disclosures.