A complex condition
People with Long COVID may experience fatigue, cognitive difficulty or ‘brain fog,’ altered smell or taste, shortness of breath, cardiovascular symptoms, muscle weakness and other problems. Symptoms and severity vary substantially.
Why inflammation
Persistent immune activation and systemic inflammation are among the mechanisms being investigated. BioVie is studying whether bezisterim’s proposed effects on inflammatory and metabolic signaling can influence fatigue and cognition.
ADDRESS-LC
ADDRESS-LC (NE3107-LC-201) is a randomized, placebo-controlled Phase 2 study designed to test whether bezisterim can improve brain fog and fatigue in people with Long COVID.
Medical guidance
This website does not provide medical advice. People with persistent symptoms should seek evaluation from a qualified healthcare professional and should not change treatment based on information presented here.
Development-stage information can change. Investigational candidates are not approved, and safety and efficacy have not been established. Review source documents and current regulatory disclosures.

